The 2025 Big 12 football season is shaping up to be one of the most exciting in recent memory. With conference realignment settled and powerhouse programs hungry for playoff contention, the schedule is packed with high-stakes clashes that will define the season. Here are 10 can’t-miss games, ranked by their potential impact on the conference title race and overall excitement.
1. Utah at Kansas State
This late-season showdown could very well decide who plays in the Big 12 Championship Game. Utah’s physical defense meets Kansas State’s balanced offense in a game that will likely have playoff implications. Both programs have been steadily rising and are looking to solidify their place among the Big 12’s elite.
2. Arizona at UCF
This might seem like an unexpected pick, but both teams are emerging threats in the conference. Arizona’s high-powered passing game clashes with UCF’s speed and electric home atmosphere. If either team is still in the title hunt by the time this game rolls around, expect fireworks.
3. Colorado at Arizona State
With Deion Sanders continuing to draw national attention, every Colorado game feels like a spectacle. This matchup against Arizona State could be a crucial swing game for bowl eligibility or even a dark horse title push. It’s also a battle of former Pac-12 foes, adding another layer of intensity.
4. Baylor at Texas Tech
The Battle for the Saddle is always heated, but this year’s edition could be especially significant. Both programs are looking to bounce back from disappointing seasons, and a win here could be the difference between a successful rebuild and more frustration.
5. Oklahoma State at BYU
Last year’s thriller ended with a dramatic double-overtime win for the Cowboys. Expect more of the same in 2025, especially with BYU now more comfortable in its second full season of Big 12 play. This game could carry major implications for the top half of the conference standings.
6. Cincinnati at Houston
A former AAC rivalry finds new life in the Big 12. While neither team was dominant in 2024, both are looking to establish a foothold in their new conference. With Houston’s explosive offense and Cincinnati’s always-tough defense, this one could go down to the wire.
7. Iowa State at West Virginia
This is a sneaky good matchup between two programs that often fly under the radar but consistently play tough, physical football. Late-season weather in Morgantown could add an extra wrinkle, and both teams are usually good for at least one major upset a year.
8. TCU at Kansas
Kansas is no longer a pushover, and TCU is trying to reclaim its 2022 form. This game could be a barometer for both teams’ seasons, with bowl positioning and bragging rights on the line.
9. Texas Tech at Utah
Altitude versus attitude. Texas Tech’s air raid faces one of the toughest defenses in the country. Expect a clash of styles and a playoff-type intensity.
10. Oklahoma State at Kansas
This one might fly under the radar, but both teams are capable of explosive offensive performances. It could turn into one of the season’s most entertaining shootouts.
From coast to mountain and everywhere in between, the 2025 Big 12 season promises drama, intensity, and plenty of can’t-miss football.
